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University of Southern California

 

Overview of Program
Clinical Training
Masters Degree Options
Research Opportunities
Collaborations
Mentorship
International Opportunites
Additional Program Highlights
Directors
Research and Clinical Interests of Directors
Current Faculty Research Projects
Clinical Training Sites

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Overview of Program

The mission of the fellowship at USC is to train fellows in a wide breadth of family planning services and research. We accomplish this by providing each fellow with a choice of flexible pathways to include research, clinical training, didactic courses and international experiences. Fellows are trained in first and second trimester abortion techniques through the Ryan Abortion Training Program located at Women's and Children's Hospital at the Los Angeles County + USC Medical Center and through Planned Parenthood of Los Angeles. In addition, experience with medical abortion is abundant through research trials and through the Ryan Abortion Training Program. The fellowship at USC has a special commitment to promoting translational research whereby answers to important family planning questions are answered through both clinical and basic science approaches. Through our Master's Program in Clinical Investigation, fellows are able to tailor a master's degree and receive credit for research and classroom time. International experiences are encouraged and designed to meet each fellow's particular interests and career goals.

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Clinical Training

Clinical training focuses on all aspects of contraception and family planning.

  • Fellows supervise and teach first and second trimester uterine evacuation techniques to the residents through the Pregnancy Options Clinic, Ryan Residency Training Program.
  • Second trimester surgical abortion training at Planned Parenthood Los Angeles with fellowship trained clinical faculty.
  • LAC+USC Women’s and Children’s Hospital serves as a referral center for genetic and complicated second trimester abortions (surgical or induction). Fellows serve as primary consultants in the care of these patients.
  • Fellow-run high-risk contraception clinic: caring for women with multiple medical problems and complicated contraception needs. Weekly patient care case conference in conjunction with clinic.
  • Surgical sterilization clinic: fellows supervise residents in laparoscopic tubal fulgurations
  • Fellows participate in general OB/GYN call (1-2 per month), supervise residents, maintain and hone teaching and practice skills.

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Masters Degree Options

Fellows complete a Master of Science in Clinical and Biomedical Investigations. The program, which draws upon the well-established educational and research resources of the Keck School of Medicine, is designed to train fellows in clinical research methods to translate clinical, biomedical and technological discoveries into advances in population-based, clinical or basic sciences research.

Eight tracks are available depending on the research interest of the fellow. Tracks include:

  • patient-oriented translational research
  • community-based intervention trials
  • design, conduct and analysis of clinical trials
  • epidemiology and disease etiology
  • health outcomes research
  • molecular biology
  • cell biology
  • alternative options

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Research Opportunities

The USC Fellowship program has a strong tradition of conducting high-quality, scientifically rigorous research. Fellows participate in ongoing clinical trials as well as in the inception and development of projects in accordance with their particular interests. Fellows have access to internationally recognized research mentors not only in the Department of Obstetrics and Gynecology but in the Departments of Preventive Medicine, Endocrinology, Pathology, Pediatrics, and others. Fellows are encouraged to utilize the experienced staff and abundant resources of the Reproductive Research Clinic (RRC) to conduct research projects.

Fellows also have access to two specialized laboratories:

  • Reproductive Endocrine Research Laboratory, under the direction of Frank Stanczyk, PhD, leader in the development of hormone assays.
  • Molecular Biology Research Laboratory:
    • PCR, ELISA, DNA/RNA extraction, histology, immunohistochemistry, numerous other basic science technologies

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Collaboration

Collaboration with other departments is strongly encouraged and facilitated through long standing relationships of the director with other faculty scientist at USC.

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Mentorship

Mentorship is provided by Dr. Mishell and is individually tailored to each fellow in the areas of professional growth and development, career planning, research. Another experienced family planning faculty mentor is being recruited.

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International Opportunities

The USC Fellowship program strongly encourages fellows to participate in an international experience and to develop a research focus to pursue while abroad.

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Additional Program Highlights

  • Faculty have a wide range of experiences and research interests.
  • Daniel R. Mishell, M.D. has great experience in the field of family planning and resident/fellow education.
  • Ronna Jurow, M.D. has great expertise in performing 1 st and 2 nd trimester abortions and is an excellent teacher.
  • Twice monthly fellows meeting for journal club and core lectures on family planning, contraception, endocrinology.
  • The Master’s program offers excellent didactic training and flexibility without monopolizing time for other fellowship experience.
  • The patient population of Women’s and Children’s Hospital is diverse and open to research participation.
  • The fellowship is set up to attend to an individual fellow’s primary goal while at the same time offering a wide range of training.
  • All former fellows from USC have gone on to obtain academic appointments.

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About the Director and other mentors

Daniel Mishell, Jr. MD is the Lyle G. McNeile Professor in the Department of Obstetrics and Gynecology of the Keck School of Medicine, University of Southern California (1978 to present) and was Chairman of this Department from 1978 to 2005. Dr. Mishell is the Editor-in-Chief of the medical journal Contraception (1970 to present). He is the Associate Editor of the Journal of Reproductive Medicine and serves on the boards of several other medical journals. He is consulting Senior Scientist for the Population Council’s International Committee for Contraception Research and helped this organization develop the Copper IUD, Norplant and the Contraceptive Ring.

The recipient of numerous awards and honors, including the Distinguished Scientist Award from the Society for Gynecologic Investigation in 1994 and the Guttmacher lectureship of the Association of Reproductive Health Professionals in 1999. Dr. Mishell has authored more than 260 scientific papers published in peer review journals and written more than 140 textbook chapters mainly on topics relating to contraception, reproductive endocrinology, and infertility. He has edited or co-edited 34 medical textbooks including Comprehensive Gynecology (4 th edition 2001), Menopause: Physiology and Pharmacology (1988), Mishell’s Textbook of Infertility, Contraception and Reproductive Endocrinology, (4 th edition 1997) and Management of Common Problems in Obstetrics and Gynecology (4 th edition 2001). In 2003 he was elected as a Fellow ad eundem of the Royal College of Obstetricians and Gynaecologists.

Ronna Jurow, MD, MS is an Associate Professor in the Department of Obstetrics and Gynecology at the Keck School of Medicine, University of Southern California, Los Angeles. Dr. Jurow came to medicine after a successful career as an opera singer, singing lead roles in Europe and the United States. She graduated from medical school at the University of California, San Francisco while simultaneously completing a Master of Science in Public Health from the University of California, Berkley. Dr. Jurow completed a residency in Obstetrics and Gynecology and a fellowship in Gynecologic Urology at the University of Southern California. Since 1984, she has been in private practice in Ventura, California with special interest and emphasis on hormones, the climacteric period, family planning, and women’s roles in society. In 1998, she returned to academics and since 2005 serves as the Director of the Family Planning Clinic and Director of the Ryan Residency Training Program. She is actively involved in teaching and mentoring the fellows and residents and is a strong patient advocate.

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Research and Clinical Interests of the Directors

  • Study of physiologic, pharmacologic and sociologic aspects of current and new methods of contraception
  • Contraceptive steroid pharmacokinetics
  • Family Planning

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Current Faculty Research Projects

  • Clinical trial evaluating the pharmacokinetics, pharmacodynamics, cycle control and safety of a year-long contraceptive vaginal ring delivering a daily dose of 150 mcg of nesterone and 15 mcg of ethinyl estradiol
  • Clinical trial evaluating efficacy, cycle control and safety of a year-long contraceptive vaginal ring delivering a daily dose of 150 mcg of nesterone and 15 mcg of ethinyl estradiol
  • Clinical trial evaluating contraceptive efficacy, cycle control, safety and acceptability of a monophasic combined oral contraceptive (COC) containing 2.5 mg nomegestrol acetate (NOMAC) and 1.5 mg estradiol (E2), compared to a monophasic COC containing 3 mg drospirenone (DRSP) and 30 mcg ethinyl estradiol (EE)
  • Clinical trial evaluating the efficacy and safety of 4-phasic oral contraceptive:estradiol valerate/dienogest in a 28-day regimen for 13 cycles in healthy female subjects
  • Clinical trial evaluating depo-medroxyprogesterone acetate use in obese and morbidly-obese women: time to return to ovulation and influence on potential mediators of the metabolic syndrome
  • Clinical trial comparing use of vaginal misoprostol to sublingual misoprostol for the medical treatment of early pregnancy failure
  • Clinical trial comparing oral vs. vaginal progesterone for combination hormone replacement therapy.
  • Clinical trial comparing follicular development in 24 vs. 21-day oral contraceptive regimens
  • Clinical trial evaluating the effect of low-dose combination oral contraceptive pill on breast milk production in exclusively breast feeding mother/infant pairs.

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Clinical Training Sites

  • LAC+USC Women’s and Children’s Hospital:
    • Reproductive Research Clinic
    • Molecular Biology Research Laboratory
    • Reproductive Endocrine Research Laboratory
    • Pregnancy Options Clinic/Ryan Abortion Training Program
    • Family Planning Clinic/High Risk Contraception Clinic
  • Planned Parenthood of Los Angele
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